John 6
41 The Jews then murmured at him, because he said, “I am the bread which came down from heaven.” 42 They said, “Is not this Jesus, the son of Joseph, whose father and mother we know? How does he now say, ‘I have come down from heaven’?” 43 Jesus answered them, “Do not murmur among yourselves. 44 No one can come to me unless the Father who sent me draws him; and I will raise him up at the last day. 45 It is written in the prophets, ‘And they shall all be taught by God.’ Every one who has heard and learned from the Father comes to me. 46 Not that any one has seen the Father except him who is from God; he has seen the Father. 47 Truly, truly, I say to you, he who believes has eternal life. 48 I am the bread of life. 49 Your fathers ate the manna in the wilderness, and they died. 50 This is the bread which comes down from heaven, that a man may eat of it and not die. 51 I am the living bread[c] which came down from heaven; if any one eats of this bread, he will live for ever; and the bread which I shall give for the life of the world is my flesh.”
52 The Jews then disputed among themselves, saying, “How can this man give us his flesh to eat?”[d] 53 So Jesus said to them, “Truly, truly, I say to you, unless you eat the flesh of the Son of man and drink his blood, you have no life in you; 54 he who eats my flesh and drinks my blood has eternal life, and I will raise him up at the last day. 55 For my flesh is food indeed, and my blood is drink indeed. 56 He who eats my flesh and drinks my blood abides in me, and I in him. 57 As the living Father sent me, and I live because of the Father, so he who eats me will live because of me. 58 This is the bread which came down from heaven, not such as the fathers ate and died; he who eats this bread will live for ever.” 59 This he said in the synagogue, as he taught at Caper′na-um. RSVCE
For many years, since I didn't believe in the Real Presence of Jesus in the Eucharist, I wasn't sure what Jesus was talking about here. But once I came to accept that Jesus was talking about the Eucharist here then other passages started to make sense as well.
Such are the miracle at Cana in John 2 where we see Jesus changing water into wine (transubstantiation) in response to His mother bringing the problem of the wedding party running out of wine. It also makes sense of His comment to her, "My hour has not yet come." The time of His offering himself up on the cross and shedding His blood which the wine signifies and becomes.
And John 16:16
16 “A little while, and you will see me no more; again a little while, and you will see me.”, when Jesus tells them that He is going away but that it is to their advantage because He will send them the Holy Spirit and they will see Him again.
And in Luke 22
14 And when the hour came, he sat at table, and the apostles with him. 15 And he said to them, “I have earnestly desired to eat this passover with you before I suffer; 16 for I tell you I shall not eat it[b] until it is fulfilled in the kingdom of God.” 17 And he took a cup, and when he had given thanks he said, “Take this, and divide it among yourselves; 18 for I tell you that from now on I shall not drink of the fruit of the vine until the kingdom of God comes.” 19 And he took bread, and when he had given thanks he broke it and gave it to them, saying, “This is my body which is given for you. Do this in remembrance of me.” 20 And likewise the cup after supper, saying, “This cup which is poured out for you is the new covenant in my blood.[c] 21 But behold the hand of him who betrays me is with me on the table. 22 For the Son of man goes as it has been determined; but woe to that man by whom he is betrayed!” 23 And they began to question one another, which of them it was that would do this.
More later.